JMJD1C and type 2 diabetes mellitus: The results of the Mendelian randomization or the JMJD1C locus (Table 2) showed that genetically predicted testosterone was negatively associated with gout (estimate = −0.757, 95% CI = −1.189, −0.324, p = 0.001) (Figure 1) and T2D (estimate = −0.262, 95% CI = −0.522, −0.002, p = 0.048) (Figure 2).