Since then, anti-programmed cell death 1 (anti-PD-1) antibodies, such as nivolumab and pembrolizumab, and anti-programmed death ligand 1 (PD-L1) antibodies, such as atezolizumab and durvalumab, have been developed and approved for lung cancer treatment [1]. The gene discussed is PDCD1; the disease is lung carcinoma.