We have studied full-length osteopontin (FL-OPN) [12] and full-length galectin-9 (FL-Gal-9) [13] in dengue patients and showed that the former directly correlated with D-dimer and ferritin levels, and the latter tracked viral load, and were associated with multiple cytokines and chemokines. The gene discussed is SPP1; the disease is dengue disease.