Bulk RNA-seq analysis of CD1c+CD14+ cells sorted from tumor-invaded lymph nodes indicated that they displayed a similar expression profile as blood DC3s (high expression of cDC2 markers such as CLEC10A and FCER1A combined with low expression of monocyte-associated markers such as C5AR1 and SOD2) (Figure 2D). The gene discussed is CD1C; the disease is neoplasm.