Patients also had non‐immunological symptoms including congenital muscular hypotonia and anhidrotic ectodermal dysplasia, which are typical of CRAC channelopathy due to LOF mutations in STIM1 and ORAI1 (Lacruz & Feske, 2015). The gene discussed is ORAI1; the disease is Anhidrotic ectodermal dysplasia.