Mutations in AIRE resulting in autoimmune polyglandular syndrome type 1 (APS1) are associated with the formation of autoantibodies against IL‐17A, IL‐17F, and IL‐22 and CMC (Lanternier et al, 2013; Mengesha & Conti, 2017). The gene discussed is AIRE; the disease is Autoimmune polyendocrinopathy type 1.