Eleven SNPs had alleles that were clearly associated with low iron, iron deficiency anaemia and/or IRIDA (SNPs in TMPRSS6 (rs855791, rs2235321, rs2235324, rs4820268, rs2413450, rs228916, rs228918 and rs228921) and TF (rs3811647, rs1799899 and rs8177253) (S1 Table). This evidence concerns the gene TMPRSS6 and IRIDA syndrome.