In addition to MS, dysfunctional RBPs, including hnRNP A1 and TAR‐DNA‐binding protein‐43 (TDP‐43), have been implicated in neurological disorders such as amyotrophic lateral sclerosis (ALS), Alzheimer's disease, and frontotemporal dementia (FTLD).3, 4, 5, 6, 7, 8, 9. The gene discussed is TARDBP; the disease is Alzheimer disease.