Nakano-Kobayashi et al. [38] reported that the oral administration of a growth inducer identified in their screen of neural stem cells (NSCs), named Algernon (for “altered generation of neurons”), which they claim has an inhibitory activity against the expression of gene DYRK1A, rescued NSC proliferation and increased the number of newborn neurons in Ts65Dn mice derived neurospheres and in human NSCs derived from human fibroblasts with DS. This evidence concerns the gene DYRK1A and Dravet syndrome.