The KM survival curves showed that the innate immune cells (DC) and adaptive immune cells (cytotoxic cells, CD8 + T cells, T cells, T helper cells and Th17 cells) displayed beneficial effect, while innate immune cells (eosinophils, neutrophils, macrophages, mast cells and NK CD56dim cells) and adaptive immune cells (Tem cells, Th1 cells and Tgd cells) displayed harmful effect on the prognosis of BLCA patients (Additional file 10: Figure S6). The gene discussed is CD8A; the disease is bladder transitional cell carcinoma.