In addition to confirming several previous cross-traits genes (e.g., DRD2 and TCF4), the present study highlighted several new ones, such as SORCS3, DCC, GLT8D1, GABBR1, and KCNB1. These genes may be risk genes with pleiotropic roles that partially underlie the common genetic architecture of multiple psychiatric disorders. This evidence concerns the gene GLT8D1 and psychiatric disorder.