This discovery, combined with our findings that the ability of HSPG2 for predicting 2-year survival is similar to that of BM blasts in AML based on the AUC value and that there was a positive correlation between HSPG2 expression and BM blasts, suggested that HSPG2 expression might be a prognostic factor for AML. This evidence concerns the gene HSPG2 and acute myeloid leukemia.