FOXP3 and thyroid cancer: While lymphocytes that are positive toFOXP3 were more found in smaller tumors (less than 2 cm), tumors without the presence of infiltration outside the thyroid gland, and cases who have concurrent chronic lymphocytic inflammation of the thyroid and concluded that FOXP3 expression had an important impact on the aggressiveness of the tumor is low-grade thyroid cancer, especially in cases with strong nuclear staining20.