It has been reported that LPO modulators alone can effectively treat multidrug-resistant cancer.75 The system \documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$${\rm{x}}^{\mbox{-}}_{\rm{c}}$$\end{document}xc-/GSH/GPX4 axis also contributes to regulation of tumor chemoresistance. Here, GPX4 is linked to neoplasm.