miR-494-3p was mainly paired with immune genes (CD3G, CXCL13, CXCR5, KLRC4), some of which had been annotated as oncogenes in leukemia including IGF1 (DRG; pan-cancer), IKZF3 (driver; leukemia), NABP1 (oncogene; leukemia), and PDGFRA (oncogene; pan-cancer). The gene discussed is IGF1; the disease is leukemia.