PTH and gout: A protective effect of uric acid (UA) on lumbar spine BMD has been reported in male patients [36] and hypothesized its potent antioxidant effect or via its interaction with the vitamin D/parathyroid hormone pathway [37], but high levels of serum UA (sUA) could cause oxidative stress and microinflammation as a pro-oxidant [38]; the role that high sUA/gout plays in OPF is also paradoxical [39–41].