Post hoc analyses revealed that within these interactions, there were significant downregulations in skin tissues of PLD fish in response to infection (uninfected L2RR = −0.01 ± 0.09, infected L2RR = −0.754 ± 0.090, p < 0.001), such that PLD-infected fish had significantly lower foxp3a expression than PSD-infected fish (PSD-infected L2RR = −0.222 ± 0.114, p = 0.020). Here, GPLD1 is linked to infection.