To examine whether MITFBSs could be associated with chromatin structure as mapped in a melanoma setting, we compiled high-confidence maps (see Methods) of open genomic regions enriched for H3K27Ac and H3K27me3 marks, indicating active or repressed chromatin, respectively, from twelve melanoma cell lines from published studies [38] and performed the same distribution analysis of MITF ChIP-seq reads in 3C- and 4C-HA-MITF cells. Here, MITF is linked to melanoma.