Among the 100 top-ranking DM CpG sites in KF compared to CF, the top seven genes were tankyrase 2 (TNKS2), hepatopoietin PCn127 (LOC723972), family with sequence similarity 45 member B (FAM45B), growth arrest specific 7 (GAS7), neuroblastoma breakpoint member 3 (NBPF3), rhomboid domain containing 2 (RHBDD2), and family with sequence similarity 64 member A (FAM64A). The gene discussed is NBPF3; the disease is cystic fibrosis.