The same lncRNA has been associated with diabetic cardiomyopathy (DCM) for it affects the expression of death-associated protein kinase 2 (DAPK2) by sponging miR-22-3p: the resulting up-regulation of DAPK2 itself leads to cardiomyocyte apoptosis in DCM [108]. Here, DAPK2 is linked to familial dilated cardiomyopathy.