Several human cancers, including B cell lymphomas, show aberrations of BRAFP1, both at genomic and transcriptional levels; Ψ-gene BRAFP1 acts as a ceRNA with BRAF in human cancer cell lines, where the silencing of BRAFP1 affects MAPK signaling and cells proliferation; BRAFP1 mouse ortholog, BRAF-rs1, shows similar oncogenic activity in in vitro settings. The gene discussed is BRAF; the disease is cancer.