In mouse CF models, circRNA-000203 was found to be up-regulated, it sponged miR-26b-5p and it was able to suppress the interaction of miR-26b-5p with Col1a2 and CTGF, to increase expression of Col1a2, Col3a1 and alpha-SMA genes and globally to eliminate the antifibrotic effect of miR-26b in this pathology [106]. Here, COL1A2 is linked to cystic fibrosis.