Promoter methylation of the genes CDH1, CDKN2Ap16, RASSF1A, TERT, and WT1 was analyzed using optimized and validated pyrosequencing assays in 14 cell lines and 151 NSCLC tissue samples, as summarized in Table 1 and Table 2. This evidence concerns the gene CDH1 and non-small cell lung carcinoma.