Functional clustering focussed on clusterin as a central gene (Figure 6C,D) showed a strong connection to genes associated with angiogenesis, complement activation (inflammatory response to myocardial ischemia), apoptotic processes, TGFβ signalling, amyloid beta homeostasis and other genes involved in protein stabilization and chaperoning. Here, TGFB1 is linked to myocardial ischemia.