Likewise, many components and signaling mechanisms of other pathways involved in cancer, such as Wnt (Wingless in Drosophila), Bone Morphogenetic Protein (BMP), Notch (N), Epidermal Growth Factor Receptor (EGFR)/Ras, Insulin, Janus Kinase/Signal Transducer and Activator of Transcription (JAK/STAT), and Jun N-terminal kinase (JNK), were delineated using fly genetics [12,13,14,15,16,17,18,19,20]. Here, MAPK8 is linked to cancer.