BLG-Lac-CML samples showed higher binding the more CML was present in the sample, which followed a stepwise increase for binding to CD36 and galectin-3, while sRAGE showed similar binding to BLG-Lac-12 and BLG-Lac-24 and only decreased for BLG-Lac-48. Here, LGALS3 is linked to chronic myelogenous leukemia, BCR-ABL1 positive.