NEXN (Nexilin F-actin binding protein), together with CSRP3 (cysteine-rich protein 3), also known as Muscle LIM protein (MLP), is shown to have important functions in foetal and adult hearts, skeletal muscle adhesion and migration during embryogenesis, and it is found to be involved in the development of cardiomyopathy [45,46]. This evidence concerns the gene CRIP3 and cardiomyopathy.