TP53 and cancer: However, we found some significantly enriched pathways associated to cancer and aging/cellular senescence such as erythroblastic leukemia viral oncogene homologue (ErbB) signaling pathway, hypoxia Inducible Factor 1 (HIF-1) signaling pathway, non-small cell lung cancer (NSCLC), pathways in cancer, phosphoinositide 3 kinase-protein kinase B (PI3K-Akt) signaling pathway and longevity regulation pathway for miR-193a-3p; while p53 signaling pathway was enriched for miR-502-3p putative target genes (Supplementary Table S3 and Supplementary Figure S2).