CLIC1 and Cognitive impairment: Table 1 shows the mean expression levels for the significant CLIC1 probe (11757474_x_at). The mean levels for the cognitive normal and mild cognitive impairment groups do not significantly differ (p-value = 0.30). However, the probable AD group has a significantly higher mean expression than the other two groups (p-value = 5.2781 × 10−7) and has a moderate to large effect size (Cohen’s d = 0.6295).