Also of notice, a pronounced number of critical immunomodulators, which were described in an immunogenomic analysis of major TCGA cancer data sets and included PDCD1LG2, BTN3A2, GZMA, BTLA, CD28, ICOS, and IDO1, were contained in the 358 DEG set [69]. The gene discussed is PDCD1LG2; the disease is cancer.