CD276 and breast cancer: On the other hand, high expression of B7-H3 mRNA was significantly associated with worse OS (HR: 1.38 (1.00–1.90); P=0.048) (Figure 2A, Table 1) and RFS (HR: 1.18 (1.01–1.38); P=0.035) (Figure 2B) in breast cancer cases.