There were 3 studies investigating an association between HLA-B*4403 and CM-induced SJS/TEN with SOC in Japanese, Brazilian, Indian, Korean and Thai populations.23,24,33–35 The numbers of subjects carrying at least one allele of HLA-B*4403 were 86 out of 293 in cases and 145 out of 1,077 in controls. Here, HLA-B is linked to toxic epidermal necrolysis.