There were 3 studies investigating an association between HLA-A*0206 and CM-induced SJS/TEN with SOC in Japanese, Brazilian, Indian and Korean populations.23,24,34,36 The numbers of subjects carrying at least one allele of HLA-A*0206 were 87 out of 250 in cases and 110 out of 948 in controls. Here, HLA-A is linked to toxic epidermal necrolysis.