IL6 and obesity due to melanocortin 4 receptor deficiency: Besides, after infection with viral agents, women produce lower levels of interleukin-6 (IL-6) compared to men, which is associated with better longevity.15 Plasma concentration of testosterone, which decreases with age, is reported to be reduced by some comorbidities, such as diabetes, obesity, and obstructive sleep apnea.16 Evidence has shown that these comorbidities are common in patients with COVID-19.