IGHE and allergic asthma: Evidences indicate that allergic asthma is attributed to the synergistical consequence of inflammatory cells (lymphocytes, eosinophils, mast cells, and macrophages), often characterized by increased biomarkers including eosinophils, serum IgE, and Th2 type cytokines (Schatz and Rosenwasser 2014; Gibson 2017).