Analyzing the tree (Figure 1a), it is possible to appreciate that it recapitulates the classical cytofluorimetric approach to B-NHL classification: CD5 is the root that divides the top part (CD5 < 32.7%) from the bottom part (CD5 > 32.7%), where there are mainly MCL and CLL, distinguished by CD200. This evidence concerns the gene CD5 and mantle cell lymphoma.