The study by Béchet [63] administered the photosensitizer chlorin conjugate with a heptapeptide (ATWLPPR), specific for the VEGFR and its membrane-bound coreceptor neuropilin-1 (NRP-1), for iPDT; they showed vascular disruption, edema in both the tumor and brain-adjacent tumor areas, and also a large decrease in VEGF expression. This evidence concerns the gene KDR and neoplasm.