In contrast to GIST T-1R cells, IM has no significant impact on the invasion and migration capacities of GIST430 cells; however, FGFR inhibitor or anti-FGF-2 Abs significantly decreased both parameters indicated above in IM-treated GIST 430 cells (Figure S3A–D). The gene discussed is FGF2; the disease is gastrointestinal stromal tumor.