PICALM and neurodegenerative disease: Nine genes were differentially spliced at multiple sites, including App, Chl1, Evl, Fus, Neo1, Olfm1, Picalm, Ppfia4 and Sorbs1. Several of these genes have been linked to neurodegeneration, suggesting that splicing dysregulation of these genes might be common to multiple neurodegenerative diseases.