Besides, there are 11 genes (PRKDC, FRY like transcription coactivator (FRYL), synaptopodin (SYNPO), Fc fragment of IgG receptor IIIb (FCGR3B), retention in endoplasmic reticulum sorting receptor 1 (RER1), CCDC73, ATPase H+/K+ transporting subunit alpha (ATP4A), contactin associated protein family member 4 (CNTNAP4), growth differentiation factor 7 (GDF7), PR/SET domain 14 (PRDM14), and EWS RNA binding protein 1 (EWSR1)) in the 17-gene signature that are validated to be a prognosis signature or strongly associated with other types of cancer already. The gene discussed is CCDC73; the disease is cancer.