The KEGG pathway analysis showed that circEIF4G2 was related to endocytosis, estrogen signaling pathway, Rap1 signaling pathway, chronic myeloid leukemia, neurotrophin signaling pathway, sphingolipid signaling pathway, chemokine signaling pathway, melanogenesis, PI3K-Akt signaling pathway, viral carcinogenesis, oxytocin signaling pathway, and ErbB signaling pathway (Figure 4(b)). This evidence concerns the gene AKT1 and chronic myelogenous leukemia, BCR-ABL1 positive.