INS and type 2 diabetes mellitus: For example, Ruan et al. [15] found that lncRNA-p3134 was associated with glucose metabolism and insulin signal transduction in pancreatic B cells; Zhao et al. [14] found that hsa-circ-0054633 provided a certain diagnostic ability for T2DM; Lin et al. [16] established a T2DM-related ceRNA network, extracted an mTOR-centered ceRNA subnetwork, and verified that lncRNA-NEAT1 may be associated with the mTOR signal transduction target protein mLST8 by binding to miR-181b.