The high expression of CDC20, PTTG2, and CDC25A was positively associated with cancer recurrence (P value = 0.02, OR: 1.72 (95% CI: 1.09-2.74); P value = 0.65, OR: 1.11 (95% CI: 0.7-1.76); and P value = 0.16, OR: 1.39 (95% CI: 0.88-2.2)), while the increased expression of GADD45A was negatively associated with cancer recurrence (P value = 0.99, OR: 1 (95% CI: 0.63-1.59), supplementary table 8). The gene discussed is CDC20; the disease is cancer.