SRC and neoplasm: In subsequent multivariate analysis, the results demonstrated that SII (HR (95% CI): 1.634 (1.121-2.382), p = 0.011), depth of tumor invasion (HR (95% CI): 1.995 (1.562-2.548), p < 0.001), lymph node metastasis (HR (95% CI): 1.481 (1.282-1.711), p < 0.001), and receipt of total gastrectomy (HR (95% CI): 0.447 (0.324-0.618), p < 0.001) were independent risk factors for gastric cancer patients with an SRC component (Table 5).