Corrected with age, education level, gender, DM duration, HBP duration, smoking, insulin usage, and metformin usage, TC and LDL are associated with TMTB, which is an index associated with executive function (β = 8.146, P = 0.030, and β = 13.704, P = 0.005, respectively) (Table 6). The gene discussed is INS; the disease is diabetes mellitus.