Tokunaga et al. [19] elucidated the clinicopathological characteristics and prognosis of AITL patients in Japan and found that patients' age >60 years old elevated white blood cell (WBC) and IgA levels; the presence of anemia and thrombocytopenia and extranodal involvement at >1 site were significant prognostic factors for OS. This evidence concerns the gene CD79A and anemia (phenotype).