MAPKAPK2 and inflammatory bowel disease: Together with our previous findings, these results suggested that MK2 was required for fMLF-induced activation of Akt, p38 MAPK, and NADPH oxidase in neutrophils, and MK2 ablation in the myeloid lineage cells had a negative impact on the activation of Akt, p38 MAPK, and NADPH oxidase, resulting in the reduction of ROS production by neutrophils, therefore alleviating IBD.