BCL2L1 and melanoma: The 2′-O-methoxyethylated Bcl-x SSO oligonucleotide is able to target the 5′-splice site in exon 2 of Bcl-x mRNA causing switch from anti-apoptotic Bcl-xL to pro-apoptotic Bcl-xS in a dose dependent manner and apoptosis via PARP cleavage in B16F10 mouse melanoma cells (Bauman et al., 2010).