Another natural drug namely indacaterol was shown to rescue SRSF6 associated aberrant splicing events, such as ZO-1 exon 23 skipping, and to reduce the viability of RKO, HCT116, and HCT8 colorectal cancer cells as well as to inhibit cancer growth in a colorectal cancer mouse model (Wan et al., 2019). The gene discussed is TJP1; the disease is colorectal cancer.