PRKAR1B and Familial prostate cancer: Specifically, the profiling of circular RNAs transcriptome in LNCaP prostate cancer cells expressing HNRNPL compared to HNRNPL-knockdown cells revealed the differential production of circ-PRKAR1B, circ-ZMIZ1, circ-FOXJ3, and circ-CCNY that have been suggested to be involved in prostate cancer development (Fei et al., 2017).