IFNG and Granuloma: Noticeably, the formation of granulomas after l‐GO exposure followed the recruitment of interstitial macrophages and moDCs, which have been previously described in granulomatous response to both sterile and infectious agents,[44, 45] and are known to stimulate Th1 polarized immune responses during granulomatous inflammation.[46] At day 7, the enhanced secretion of both IL‐6 and IFN‐γ was also an event favoring a Th1 response to l‐GO.