Furthermore oleic acid has been shown to inhibit tumour cell proliferation in a dose- and time-dependent manner, inducing cell cycle G0/G1 arrest, increasing the apoptosis and the expression of p53 and cleaved caspase-3, and decreasing the expression of CyclinD1 and Bcl-2 (Jiang et al., 2017). This evidence concerns the gene TP53 and neoplasm.