Among those favorable prognosis-related molecules, the anti-HCC activity of RAD52 motif 1 (RDM1), adipose triglyceride lipase (ATGL) and growth arrest-specific protein 2 (GAS2), and microRNA-34a and microRNA-621, was mainly associated with increased p53 function (transcription and activating p53 pathway). This evidence concerns the gene RDM1 and hepatocellular carcinoma.