SUSD2 and neoplasm: OVCAR3-NT mice displayed a modest, yet significant increase in median survival when compared to the OVCAR3 sh2 mice (175 days vs. 185.5 days, respectively; p-value = 0.005 [Matnel-Cox]; Figure 6D), suggesting that decreased SUSD2 expression in HGSOC predicts decreased overall survival, consistent with our metastatic analysis (IHC and UBM analyses) performed on mice from Experimental Arm 1. IHC analysis was also performed on mouse organs harvested from mice in Experimental Arm 2, demonstrating an increase in overall tumor burden when compared to that observed in mice from Experimental Arm 1.