As shown in Figure 4, compared with sham group, the relative expression levels of ANP, BNP, and β-MHC mRNA in AAC group were increased significantly; however, compared with AAC group, the relative expression levels of the three myocardial hypertrophy genes in AC 250 and 500 mg/kg groups were decreased significantly. The gene discussed is NPPB; the disease is cardiac hypertrophy.