The results of pre-chemotherapy evaluation showed that of the 98 patients examined, only two cases including one patient with ALL and another with lymphoma, had a positive IgM titre of above 1 IU/ml and 46 [46.9% (95% CI 37.4–56.7)] cases had positive IgG titers, 20 [43.5% (95% CI 30.2–57.8)], 15 [50% (95% CI 33.2–66.8)] and 11 [50% (95% CI 30.7–69.3)] of whom were patients with AML, ALL and lymphoma, respectively. The gene discussed is CD40LG; the disease is acute myeloid leukemia.